Sweden : PhD position in Medical Science in the research group of Hematology

Uppsala University hereby declares the following position to be open for application:

PhD position in Medical Science in the research group of Hematology

at the Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, starting date as soon as possible, but no longer than 4 years.

The department of Immunology, Genetics and Pathology at Uppsala University (http://www.igp.uu.se) has a broad research profile, with several strong research groups in different fields of science, e.g. medical and clinical genetics, bioinformatics, immunology, pathology, tumour biology, vascular biology and method development. The department was founded to promote a closer collaboration between clinical and pre-clinical research and part of the activity is integrated with the clinics of genetics and pathology-cytology at the University Hospital, Uppsala. Rudbeck Laboratory has access to state-of-the-art technologies, with core facilities for cell analysis, confocal microscopy, DNA-sequencing and genotyping.

Project description: We are looking for a student who wants to study for a PhD degree in the field of tumor biology and hematology. The main project will be to investigate epigenetic mechanisms in the biology of multiple myeloma. Characterization of tumor specific genes for tumor initiation and steaminess regulated by DNA and histone methylation will be identified in patient material and in cell lines genetically engineered by by lentiviral vectors for shRNA. The project includes ChIP- sequencing and functional validation of candidate mechanisms and target genes in models of myeloma in vitro och in vivo. Methods applied are in vitro and in vivo models of multiple myeloma, cell- and molecular biological methods including ChIP, lentiviral transfer, use of annotated drug libraries and RNA based gene profiling. Previous experience in epigenetic research is appreciated. Further information on the activity of the research group can be accessed at;

http://www.igp.uu.se/Research/Hematology/helena_jernberg-wiklund/

The successful candidate will devote most of the time towards his/her research level education. Other service activities within the department, e.g. education and administrative work can be included within the framework of the employment (maximum 20%).

Qualifications: The applicant should have an academic degree, e.g. MSc Pharm, or MSc Molecular Biology, or similar. Experience from experimental research, epigenetic methods, flow cytometry, and in vitro and in vivo models of hematopoeitic tumors are considered as additional qualifications. Documented skills in oral and written English are required.

The application should include a curriculum vitae, copies of exams, degrees and grades, references and a short description of the applicant and his/her experience. Letters(s) of recommendation may be included. If the applicant has published scientific papers, they can also be included.

Information about education at the postgraduate level, admission requirements and admission decisions can be found at www.medfarm.uu.se/forskarutbildning/index.shtml.

Selection of applicants will be done by the future tutor for the selected student in consultation with the postgraduate study group of the department. The Postgraduate Programmes Committee at the Disciplinary Domain of Medicine and Pharmacy will formally approve the student’s admission.

Setting the salary will be according to local guidelines at Uppsala University.

The rules governing this process can be found (in Swedish) in Högskoleförordningen 5 Chapter 1-7 §§ and in University rules http://regler.uu.se/.

For further information about the postgraduate position contact Helena Jernberg Wiklund, tel.+46184714812 or e-mail helena.jernberg_wiklund@igp.uu.se
Union representatives are: Anders Grundström, Saco-council, tel. +46184715380, Carin Söderhäll, TCO/ST, tel. +46184711996, and Stefan Djurström, Seko, tel. +46184713315.

You are welcome to submit your application no later than February 3, 2012, UFV-PA 2012/188. Use the link below to access the application form.

Further Information

Application Deadline : 3 February 2012

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Posted on 2012-01-29 18:56:02

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The announced deadline for above scholarship is expired and new applications may no longer be accepted. The notice is available for reference purpose only.

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