Project Title: The genomic architecture of human nucleolar organizer regions and its role in nucleolar biology
Supervisor: Prof Brian McStay
Duration: Funded for 4 years (Structured PhD), full-time.
Project description: Nucleoli form around arrays of genes that encode the major RNA component of ribosomes. These ribosomal gene arrays, known as nucleolar organizer regions (NORs) are located on the short-arms of five human chromosomes. Contrary to popular belief the human genome sequence is incomplete and missing regions include the NOR bearing short arms of human chromosomes 13, 14, 15, 21 and 22. The successful candidate will join a Wellcome Trust funded team that aims to describe the genomic architecture surrounding human NORs (see recent publications Floutsakou et al. 2013. Genome Res 23: 2003-2012 and Grob et al. 2014. Genes Dev 28: 220-230).
Stipend: €16,000 per annum & fees for 4 years.
Entry Requirements: Applicants should have a good primary degree (First or Second Class Honours) or M.Sc. in an appropriate discipline (Biochemistry, Genetics, Molecular Biology etc.). The successful candidate should be highly self-motivated. Previous research is also an advantage but is not essential.
Expected start date: 1st September 2015
How to apply: Please send a letter of introduction, a 400 word statement on your research ambitions and a current CV, indicating your research experience and including the names of two referees to Professor Brian McStay via email to firstname.lastname@example.org
Closing date for applications: 5pm on Friday 10th April 2015.
For further information on the CCB and Prof McStay see http://www.chromosome.ie/ and http://www.nuigalway.ie/biochemistry/staff/mcstay/index.html.
Application Deadline : 10 April 2015
Posted on 2015-03-17 22:18:07
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