We are looking for a graduate student in Chemistry with specialization in Organic Chemistry
Description of the project
Many novel drug targets, in particular protein-protein interactions, cannot be modulated with small drug-like molecules. Instead, compounds in a different chemical space, e.g. macrocycles and peptides, are required for such “difficult targets”. We have built a significant knowledge base on properties required for compounds to bind to difficult targets while also being cell permeable. The project aims to expand our knowledge by synthesis of macrocycles that have been designed to study key properties, such as their target binding affinity and cell permeability. It will be carried out in collaboration with AstraZenca R&D Gothenburg.
The PhD position is for four years, extendable to a maximum of five years by including department duties, typically teaching.
Nature of duties
The PhD student is expected to carry out advanced research in organic chemistry and to broaden his/her perspective and knowledge of organic chemistry by taking graduate courses in relevant subjects. The student is also expected to teach and participate in general departmental work, such as instrument maintenance, to a level corresponding to a maximum of 20% of the employment time. Since first year undergraduate courses are taught in Swedish, proficiency in Swedish may be considered an advantage.
Here you can read about our post graduate studies.
Rules governing PhD candidates are set out in the Higher Education Ordinance Chapter 5, §§ 1-7 and in Uppsala University's goals and guidelines.
To qualify for a PhD position the applicant must have at least 240 credits (hp), or an equivalent basic university education, with at least 90 credits in chemistry and 60 credits at the advanced level. At least 40 credits must be in organic chemistry at the advanced level. Applicants from outside the European Union must provide the results from a GRE general test.
It is desired that you have a science master´s degree in organic or medicinal chemistry, or similar experience. Strong knowledge in synthetic organic chemistry is required, and some experience in computational and/or medicinal chemistry is and advantage.
We place great emphasis on your personal qualifications. You need to have a strong motivation for the research project and to be able to contribute with creative ideas. This project requires that you are able to work independently, but that you also have excellent collaborative skills as the project will be run in close collaboration with scientists at AstraZeneca. You also need good language skills in English in order to be able to interact and publish internationally.
Criteria for ranking
The ranking of applicants will be based on undergraduate grades, on the undergraduate education profile and on any additional experience of research in areas of relevance for the research project. Such additional experience should be demonstrated, e.g. through articles published in international peer reviewed journals or by employments at companies or institutions active in the field of research. High emphasis will also be put on personal qualifications required for the project.
In filling this position, the university aims to recruit the person who, in a combined evaluation of competence, skills and documented qualifications, are judged most suitable to carry out and develop the project-in-hand and to contribute to a positive development of the department of chemistry. Interviews will be performed with the top candidates through visits to Uppsala University and/or AstraZeneca, or by electronic means.
Your application must include a personal letter with a short description of yourself and your specific areas of interest in research. You must also include a CV, authorized copies of degrees and diplomas, copies of your bachelor or master thesis and other documents, such as publications, that you want to invoke. Names and contact details of at least two scientists that have accepted to act as references for you must also be included.
Uppsala University aims for gender balance and diversity in all activities in order to achieve a higher quality at all levels of the organization. We therefore welcome applicants of any gender and with different birth background, functionality and life experience.
Application Deadline : 15 August 2016
Posted on 2016-06-26 03:31:07
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