The chemistry research at BMC focuses on issues related to catalysis, molecular recognition, and complex molecular systems structure and dynamics, and the correlation between the presence of chemical compounds and biomolecules with various disease states. There is also a strong research in methodology and technology, including the design and synthesis of small organic molecules and biological macromolecules. Development of new biochemical and analytical methods are the basis for advanced study of biological systems and their regulation and how diseases can be diagnosed and treated. Scientists with expertise in mass spectrometry and biophysical methods of interaction analysis operate in the SciLifeLab facilities for proteomics and drug discovery. You can find more information about us here.
We are hiring a PhD student to work within the biochemistry research programme as part of one of our projects.
Description of our project:
Recent technological advances in mass and ion-mobility spectrometry have enabled new means for studying the structure, dynamics, and interactions of macromolecules (structural proteomics). This includes membrane proteins and polydisperse proteins that for different reasons are difficult or impossible to study using traditional methods for structural biology. The purpose of the project is to realise the potential of this type of experiments and to apply them in order to get a structural understanding of the function of proteins that are of interest for both drug development and basic science. As part of this work, new tools need to be developed for creating a more immediate connection between theory and experiment. Computations as well as obtaining experimental data will in part take place within international collaboration with other research groups at the forefront of their respective fields.
The PhD student is expected to carry out advanced research in biochemistry and related disciplines, and deepen as well as broadening his or her knowledge of chemistry by taking graduate courses in relevant subjects. The can also be expected to take on general departmental work, such as equipment maintenance and teaching, to an extent corresponding to a maximum of 20% of the student’s employment time.
Applicants must hold an MSc in natural science or similar. Good knowledge regarding theoretical chemistry, molecular modelling, programming, protein chemistry, mass spectrometry, and structural biology is advantageous. For an applicant to succeed as a PhD student with us, should he or she be selected, he or she needs to be highly motivated with regards to the research, and must be able to work independently with their part of the project. Since the project involves work within collaborations, and because we place great value in that all co-workers contribute to a good working environment, applicants must also be able to cooperate with close colleagues as well as researchers at other departments. We value new ideas, and good applicants thus have a creative mind-set in order to find new approaches to the research problems we aim to solve. In order to interact and publish on an international arena we require applicants to be proficient English speakers and writers. Personal suitability will be a significant factor in the application process.
Your application must include a personal letter with a brief description of yourself and your research interests. The application must also contain a CV, copies of diploma and degrees, bachelor or master thesis, and other documents you wish to invoke.
Rules governing PhD candidates are set out in the Higher Education Ordinance Chapter 5, §§ 1-7 and in Uppsala University's goals and guidelines.
Uppsala University aims for gender balance and diversity in all activities in order to achieve a higher quality at all levels of the organization. We therefore welcome applicants of any gender and with different birth background, functionality and life experience.
Application Deadline : 15 October 2016
Posted on 2016-09-06 12:48:46
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